Immune checkpoint inhibitors have transformed cancer care to the point where the popular Cox proportional-hazards model provides misleading estimates of the treatment effect, according to a new study published April 15 in JAMA Oncology.

A machine learning algorithm that predicts suicide attempt recently underwent a prospective trial at the institution where it was developed, Vanderbilt University Medical Center.

Statewide stay-at-home orders put in place as Tennessee fought to control the spread of coronavirus last March were associated with a 14% lower rate of preterm birth, according to a research letter published today in JAMA Pediatrics.

In a large-scale study of electronic health records, Vanderbilt University Medical Center investigators have determined the prevalence of functional seizures and characterized comorbidities associated with them.

Neurosurgery is a complex and intricate process, and it is important to continuously refine and seek innovative techniques to make it safer, gentler and more precise and effective.

The rate of mothers who had an opioid-related diagnosis when delivering their baby increased by 131% from 2010-2017, as the incidence of babies diagnosed with drug withdrawal, known as neonatal abstinence syndrome (NAS), increased by 82% nationally during that same time period.

Vanderbilt University Medical Center (VUMC) researchers are enrolling adults age 75 and over to study whether taking atorvastatin, a drug commonly used to lower cholesterol, also called Lipitor®, can help maintain health by preventing dementia, disability, and heart disease.

Early alcohol consumption increases risk of miscarriage, according to new Vanderbilt-led study.

It's hard to stop what you don't understand. The American College of Surgeons has secured a grant to identify individual & community risk factors for non-lethal firearm injuries.

In a major public health success, the introduction of pneumococcal conjugate vaccine PCV13, or Prevnar 13, in 2010 in the United States is associated with reduction in socioeconomic disparities and the near elimination of Black-white-based racial disparities for invasive pneumococcal disease.

A lower body mass index (BMI) does not protect smokers from fat-associated health risks, according to a Vanderbilt University Medical Center (VUMC) study published in PLOS Medicine.

One-third of Tennessee parents with children ages 6-17 are worried their child has an undiagnosed mental health condition, a new poll from the Vanderbilt Center for Child Health Policy found.

The innovative All of Us initiative from the NIH provides researchers with a rich source of data to speed discoveries in both precision medicine and population health.

Researchers at Vanderbilt University Medical Center's (VUMC) Center for Biomedical Ethics & Society were recently awarded a grant from the National Human Genome Research Institute (NHGRI) of the National Institutes for Health (NIH) to explore LGBTQ+ perspectives on a range of issues related to biomedical research.

Pregnant women involved in the criminal justice system are disproportionately not receiving medications for opioid use disorder, as compared to their peers, according to a Vanderbilt-led study published today in PLOS Medicine.

People who received information from the Screen to Save program, a culturally tailored initiative from the National Cancer Institute (NCI) Center to Reduce Cancer Health Disparities (CRCHD), increased their knowledge of colorectal cancer and indicated willingness to adopt potentially preventive behavior changes.

Faced with a global pandemic of a virus previously unknown to humans, the National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health has launched a clinical trial to understand if hydroxychloroquine, a well-known drug used for malaria and rheumatologic conditions, is safe and effective in treating hospitalized adults with COVID-19.

A decade after the passage of the Patient Protection and Affordable Care Act (ACA) of 2010, there is evidence that the landmark health care legislation has contributed to slower growth of U.S. health care spending.

Also approves $16.4 million for new studies on maternal depression, HIV prevention, prostate cancer and care transitions

Most Tennessee infants exposed to hepatitis C at birth are not later tested to see if they acquired the virus, according to a study by researchers at Monroe Carell Jr. Children's Hospital at Vanderbilt and the Vanderbilt Center for Child Health Policy.

A molecule produced by the brain that activates the same receptors as marijuana is protective against stress by reducing anxiety-causing connections between two brain regions, Vanderbilt University Medical Center researchers report.

Zebrafish, pediatric patients and DNA biobank-linked electronic health records inform research study