Archives     Advertise     Editorial Calendar      Advertiser Index     Subscribe     Contact Us    


Statins to be Studied for Prevention of Dementia, Disability, and Heart Disease


 
Amanda Mixon, MD

Vanderbilt University Medical Center (VUMC) researchers are enrolling adults age 75 and over to study whether taking atorvastatin, a drug commonly used to lower cholesterol, also called Lipitor®, can help maintain health by preventing dementia, disability, and heart disease.

The PREVENTABLE (Pragmatic Evaluation of Events and Benefits of Lipid-Lowering in Older Adults) study is one of the largest trials ever conducted in older adults and will include more than 20,000 participants and 100 sites across the U.S.

Participants will be followed for up to five years using electronic health records, Medicare data, and telephone study visits.

The study drug will be shipped directly to participants' homes every three months.

"Few studies have focused exclusively on individuals age 75 or older," said VUMC principal investigator Amanda Mixon, MD, assistant professor of Medicine in the Division of General Internal Medicine and Public Health.

"While statins have been shown to reduce the risk of cardiovascular events for some patients, PREVENTABLE will help us to learn whether they are helpful for older adults without heart disease," she said.

In addition to learning whether statins can prolong health in older adults, the PREVENTABLE study will help clarify which older adults should not be taking statins.

"Patients often ask me what they can do to stay healthy and prevent dementia," said PREVENTABLE principal investigator Karen Alexander, MD, a geriatric cardiologist at Duke University Medical Center. "This study will help to clarify the benefit of statins for this population. This is important to do before adding one more medication to the list of medicines older adults are often already taking. Results from this study will help us provide valuable answers to improve how we age."

PREVENTABLE is funded by the National Institute of Aging and the National Heart, Lung, & Blood Institute of the National Institutes of Health under award number U19AG065188.

For more information, contact VUMC study coordinator Ashley Ehlert at (615) 875-7964 or ashley.ehlert1@vumc.org.

 
Share:

Related Articles:


Recent Articles

Blackburn, Duckworth Lead Bipartisan Legislation to Improve Lives of People with Limb Loss

U.S. Senator Marsha Blackburn (R-Tenn.) introduced bicameral, bipartisan legislation along with Senator Tammy Duckworth (D-Ill.) to improve health outcomes for individuals living with limb loss or limb differences.

Read More

Method Proposed to Correct Misinterpretations of Long-Term Survival Rates for Immunotherapies

Immune checkpoint inhibitors have transformed cancer care to the point where the popular Cox proportional-hazards model provides misleading estimates of the treatment effect, according to a new study published April 15 in JAMA Oncology.

Read More

Blackburn, Durbin Introduce Legislation to Improve Rural Health Care

U.S. Senator Marsha Blackburn (R-Tenn.) along with Senators Dick Durbin (D-Ill.), Lisa Murkowski (R-Ala.), and Tina Smith (D-Minn.) introduced the bipartisan Rural America Health Corps Act. Representatives Cheri Bustos (D-Ill.) and David Kustoff (R-Tenn.) introduced companion legislation in the House of Representatives.

Read More

AHA Statement On Senate Passage Of Medicare Sequester Relief Legislation

Read More

Crucial Behavioral Health Bill Introduced

Reps. Dan Kildee (D-Mich.) and Brad Wenstrup (R-Ohio) introduced their bipartisan bill, the Rural Behavioral Health Access Act.

Read More

New Analysis Shows Continued Negative Impact Of COVID-19 On Hospital & Health System Financial Health In 2021

A new analysis prepared by Kaufman, Hall & Associates, LLC and released by the American Hospital Association (AHA) highlights the ongoing consequences of the COVID-19 pandemic on the financial stability of hospitals and health systems, threatening their ability to continue to provide essential services to their patients and communities.

Read More

NAACOS Asks HHS Secretary Xavier Becerra to Grow Medicare ACO Programs

Letter Recommends National Goal to Have a Majority of Traditional Medicare Beneficiaries in an ACO by 2025

Read More

Luck of the Irish

Read More

Artificial Intelligence Calculates Suicide Attempt Risk

A machine learning algorithm that predicts suicide attempt recently underwent a prospective trial at the institution where it was developed, Vanderbilt University Medical Center.

Read More

Pre-term Births in Tennessee Decreased During Pandemic

Statewide stay-at-home orders put in place as Tennessee fought to control the spread of coronavirus last March were associated with a 14% lower rate of preterm birth, according to a research letter published today in JAMA Pediatrics.

Read More

Email Print
 
 

 

 


Tags:
None
Powered by Bondware
News Publishing Software

The browser you are using is outdated!

You may not be getting all you can out of your browsing experience
and may be open to security risks!

Consider upgrading to the latest version of your browser or choose on below: